IDENTIFICATION AND EVALUATION OF ANTIVIRAL ACTIVITY OF NOVEL COMPOUNDS TARGETING SARS-COV-2 VIRUS BY ENZYMATIC AND ANTIVIRAL ASSAYS, AND COMPUTATIONAL ANALYSIS

The viral genome of the SARS-CoV-2 coronavirus, the aetiologic agent of COVID-19, encodes structural, non-structural, and accessory proteins.Most of these components undergo rapid genetic variations, though to a lesser extent the essential viral proteases.Consequently, the protease and/or deubiquitinase activities of the cysteine proteases Mpro and

Among the significant challenges facing social sciences seriously is the resting of these sciences on a series of foundations not only far from divine thought, but contrasting it in certain cases.The very point gives rise to these sciences solving social problems in a non-divine paradigm.Among the different fields of foundations, anthropological fo

Introduction: Rose (Rosa hybrida (L.), Rosaceae) has been grown on earth for millions of years and has been used for beauty and decoration of gardens, extraction of perfume and in medicine.But main use of roses is in cut flower industry and landscaping.Roses are attractive for insects, especially aphids (2, 3, 5, 6, 7, 11, 17, 27, 28, 35, 38).Among

As the main body of resource aggregation, virtual power plant (VPP) not only needs to participate in the external energy market, but also needs to optimize the management of internal resources.Different from other energy storage systems, hydrogen energy storage systems can participate in the hydrogen market in addition to the backup and supplement

ABSTRACT An investigation was made into the effects of different lairage times and the position of chicken crates during transport to the slaughterhouse on the biochemical and hematological profile and physical parameters of broilers, such as color and pH of their breast meat.The treatments were defined by the animals slaughtered after 0, 2, 4 and